The prostate is divided into several anatomic regions, or zones. Most prostate cancer develops from the peripheral zone near the rectum. That’s why a digital rectal exam (DRE) is a useful screening test.

Benign prostatic hypertrophy (BPH), a non-cancerous prostate condition, typically develops from the transition zone that surrounds the urethra, or urinary tube. This is why BPH causes more difficulty with urination than prostate cancer typically does.

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